Exercise Induced Collapse

What is Exercise Induced Collapse?

Exercise Induced Collapse (EIC) is a genetic disorder primarily found in dogs, especially within certain breeds. As the name suggests, dogs with this condition have episodes triggered by intense exercise, where they lose control of their rear limbs, resulting in a collapse.

Causes of Exercise Induced Collapse

EIC is caused by a mutation in the gene known as the DNM1 gene. This gene is responsible for nerve signal transmission to the muscles. When this gene is mutated, these nerve signals become interrupted during times of intense exercise, leading to a loss of control and eventual collapse.

Symptoms of Exercise Induced Collapse

The most apparent symptom of EIC is a sudden, dramatic loss of muscle control following periods of strenuous activity. However, there are several other signs that may be associated with Exercise Induced Collapse, including abnormal gait, dragging of the hind legs, inability to rise, and in severe cases, temporary paralysis. Signs of EIC usually appear within 5 to 20 minutes of starting intensive exercise.

Diagnosis and Treatment for Exercise Induced Collapse

Diagnosing EIC involves genetic testing to detect the presence of the mutated DNM1 gene. Currently, there is no cure for EIC, but there are steps owners can take to manage the condition and provide a good quality of life for their dogs. Management may include controlling exercise levels, avoiding triggers, and in some cases, medication may be prescribed to help control the symptoms.

Prevention of Exercise Induced Collapse

Prevention of EIC is possible through responsible breeding practices. Since EIC is a genetic disease, dogs who have tested positive for the gene mutation should not be bred. By doing this, the spread of the DNM1 mutation responsible for Exercise Induced Collapse can be controlled and significantly minimized.